mhhh… I don’t know / think so.
All the controllers, whether S1 or S6 or in between, are based on EUCON.
So all the software interfaces (the core) between EUCON and Steinberg software should be the same, whether a S1 or S6 is communicating.
I also asked in the DUC forum and Eddie replied S6 and Nuendo 10 - Avid Pro Audio Community
I think the bugs exist with all of the AVID / EUCON controllers.