That’s the mobo I have and it doesn’t work out of the box. I’m still trying to find if you can set the PCIe slots back to 3 so it will work. I’ll post back when I know one way or the other.
Here’s a X570 mobo with PCIe3. This is my option if I can’t make my UAD2 Quad work with my ASrock X570 Extreme4:
https://www.newegg.com/asu-rog-crosshair-viii-hero/p/1JW-000C-00H64