New UR44C, new to this, nothing works

I do not know about the 44 becasue I have the UR816C, but I launched my Guitarrig for a moment and choose the Asio USB URC and everything works as it should be. ALso in Cubase under devices no problems. I never use any windows audio menu, don’t know why I should.
You always choose the driver and it’s adjustments in the particular audiosoftware you use, f.e. your DAW or in this case Guitarrig.
If Cubase & Guitarrig give a message that your device is not present I would install the whole driversoftware again. There must be something wrong or not installed at the correct place?
Are you using W10?