You can uninstall the USB driver with the uninstall-routine in the original pkg.
I have no “benchmark” though, in order to test how powerful this “set-up” is (meaning: with not heaving installed the driver).
It could affect latency (there was a significant / detectable latency I could feel, when using my midi piano) and also sound quality.
Why does one need the proprietary driver in the first place, if it runs better without any driver on mac?
It is a little bit complicated.
Things are easier on ipad and (for the moment) on Win 10.
But I thought, this soundcard would also work on a mac, heaving the proprietary diver installed.
I don’t use cubase.
To be honest, this resembles a little bit the bad experiences I made with the support of steinberg / cubase.
You should assume, that a 150€ device has a working driver for the newest mac catalina, but it doesn’t.
You can wait for your reply for a long time, I guess.