I am having the exact same problem with the UR 22mkII.
All of a sudden it is recording output channels, click tracks etc.
I have deleted and reset up new Buses when i’ve had similar problems but its having no effect.
It has also started happening on Template projects where it was previously set up perfectly.
If there is a loopback mode I cannot find it to toggle it off but i very much doubt it is that. I havent changed a single thing to my set up.
It is so annoying!