I have the same problem.
Artist 9.5 has been working fine for me since I updated.
Today I randomly got a couple of error messages when i tried to start up “Unknown Application not registered”.
Cubase still launched, but now it freezes everytime i hit play.
I’m running with an i7-6700K, 64 gigs of ram and a 1080 GPU, so I feel like this shouldn’t happen.