CMC-CH global bypass not working on 8.5.1 Pro

I have the same specs and can confirm that the buttons in question work as they should on any audio track. I’m confused however by your reference to “global”. These command buttons affect the selected 'CH’annel only and are not forseen with Shift functions. You could assign new key-commands for these global bypass commands to the F4,6,8 user commands of the CMC-CH and they would be activated by pressing the shift and the button to the left of the intended button (the commands are in the mixer category). That’s about the closest you’d get.