Has anybody tried N10.3 in Windows 7?

You can create a new template, or build new signal chains, or import tracks from any project,
including tracks from older Nuendo 4.3, for example.
So throughout the years, compressors, EQs, Effects, Subgroups and complete signal chains
become consistent, even if you redesign your new template.

That being said, you may be referring to Settings, which can make the newer versions unstable
if imported from older versions.