Up until last year I was running an n12. Great sounding interface. It works fine with Cubase. I used it with Cubase 9 or 9.5 I think. You need to do all the firmware upgrades and load the templates into Cubase. All the transport functions should work as well as markers and metronome. Other things as well but I can’t remember. There is also presets for the compression. I remember I would sometimes use hardware mixing to add the n12 reverb and use the compression as it was to my ears much smoother than the stock Cubase plugins. I was using with the full pro Cubase version. I never used the AI version that came with it.