i04 missing ports Cubase Elements 9.5

Can anyone help please. For some reason my Cubase Elements 9.5 isn’t recognising the Alesis i04. I’m getting a missing ports message. Can’t understand why this is suddenly happening it’s been working fine. I’ve checked all the audio connections on the system any ideas where I should go to dig deeper?
Cheers
Chris

Correct ASIO driver selected?

Cubase Pro 9.5 missing ports message everytime i boot up. It’s been working fine and suddenly…any ideas anybody please? It appears the Cubase programme isn’t recognising Alesis i04