Any disadvantages from using Nuendo over Cubase?

I am using Cubase at present for music and some sound design, and Davinci Resolve for video editing/grading. I have used the Fairlight sound mixing component of Davinci Resolve very successfully and I do like it because it makes selecting channels from a multichannel file easy and is part of an integrated suite, but, it is lacking in some areas, however, round tripping to Cubase can be a bit frustrating (doesn’t support MXF for example) and channel selection from a multichannel file isn’t straight forward, so I find myself having to work in multiple packages.

So my question is whether Nuendo works nicely with import / export to NLE’s, handles multichannel files with ease and whether it will open / save Cubase projects (or are cubase projects one-way)?