Just got my S49 Mk2 and i’m loving the integration. Transport works perfectly, scrub works sweet, loop, quantize. I’m not having any problems with the mixer page and using things like mute/solo. Worked straight out of the box and works very well. Selecting a track with buttons on the mixer page takes you directly there in Cubase, so enabling you to quickly select a track, adjust the volume, write automation or record a part. I’ve also setup some custom assignments to the eight upper buttons, with labels, to set things like auto quantize, quantize up/down etc. Loving its simple layout and minimal controls tbh.