What is the best location to save projects in my situation?

Projects, especially with midi only data take up very little storage space. Once you start to export your tracks to audio and especially to 96khz and above you’ll need a lot more storage and with an extreme amount of tracks and plugins you may notice performance needs will increase also. In your case I would just put them on the 5400rpm drive. Even these drives are in general fast enough to handle tens of audio tracks simultaneously. You can test this yourself by creating a test project and increase the number of audio tracks and see how far it will go?