UR 22 MKII for Live Performance

I’m looking to upgrade my current interface with the ur22 mkii. I currently run an old Line 6 UX1 together with a Microsoft Surface Pro and Amplitube 4 guitar program. The interface has two analog outputs (1/4 in.) one of which is dedicated to mono. From there it connects to the effects loop of an amp head and played through an frfr cab. This gives me everything I need as far as output for an informal band jam. My question is can this setup be replicated using the ur22 mkii?