Setting up with Nuendo 4

Hi there. I would really appreciate it if someone could take the time out to help me get set up correctly with my hardware and software. I am new to Nuendo. Although I have used cubase in the past, I am only familiar with the basics and not very clued up on the whole setup side of things. Im using a PC running Nuendo 4, a Lexicon Lambda usb audio interface, an older Oxygen 8 midi keyboard and also a Line 6 FBV shortboard Mk 2.
I have pics of the equipment and some screenshots I took from inside Nuendo if they are any use.